Lagos bat virus transmission in an Eidolon helvum bat colony, Ghana

Freuling, Conrad Martin GND; Binger, T.; Beer, Martin GND; Adu-Sarkodie, Y.; Schatz, Juliane GND; Fischer, Melina GND; Hanke, Dennis GND; Hoffmann, Bernd GND; Höper, Dirk GND; Mettenleiter, Thomas C. GND; Oppong, S.K.; Drosten, C.; Müller, Thomas GND

A brain sample of a straw-coloured fruit bat (Eidolon helvum) from Ghana without evident signs of disease tested positive by generic Lyssavirus RT-PCR and direct antigen staining. Sequence analysis confirmed the presence of a Lagos bat virus belonging to phylogenetic lineage A. Virus neutralization tests using the isolate with sera from the same group of bats yielded neutralizing antibodies in 74% of 567 animals. No cross-neutralization was observed against a different Lagos bat virus (lineage B).

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Freuling, Conrad Martin / Binger, T. / Beer, Martin / et al: Lagos bat virus transmission in an Eidolon helvum bat colony, Ghana. 2015.

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